GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs7611238 | 1 | rs13072826 | chr3:195064755 | C3orf21 | chr3:194789015-194991895:- | 0.28 | 5.33 | 1.66E-7 | Body mass index |
| BLCA | cis | rs3796352 | 1 | rs13076033 | chr3:52898427 | TMEM110 | chr3:52867139-52931547:- | 0.41 | 3.85 | 0.000138 | Immune reponse to smallpox (secreted IL-2) |
| BLCA | cis | rs10935120 | 1 | rs13081177 | chr3:134289860 | ANAPC13 | chr3:134196547-134204865:- | -0.51 | -8 | 1.53E-14 | Height |
| BLCA | cis | rs10935120 | 1 | rs13081177 | chr3:134289860 | CEP63 | chr3:134204575-134293852:+ | -0.25 | -4.25 | 2.73E-5 | Height |
| BLCA | cis | rs10935120 | 1 | rs13081688 | chr3:134259954 | ANAPC13 | chr3:134196547-134204865:- | -0.5 | -7.96 | 2.01E-14 | Height |
| BLCA | cis | rs10935120 | 1 | rs13081688 | chr3:134259954 | CEP63 | chr3:134204575-134293852:+ | -0.24 | -4.2 | 3.39E-5 | Height |
| BLCA | cis | rs9815354 | 1 | rs13087719 | chr3:41951576 | ULK4 | chr3:41288091-42003660:- | -0.63 | -9.74 | 3.43E-20 | Diastolic blood pressure |
| BLCA | cis | rs10935120 | 1 | rs13087875 | chr3:134261123 | ANAPC13 | chr3:134196547-134204865:- | -0.5 | -7.97 | 1.89E-14 | Height |
| BLCA | cis | rs10935120 | 1 | rs13087875 | chr3:134261123 | CEP63 | chr3:134204575-134293852:+ | -0.24 | -4.09 | 5.33E-5 | Height |
| BLCA | cis | rs10935120 | 1 | rs13089966 | chr3:134279197 | ANAPC13 | chr3:134196547-134204865:- | -0.5 | -7.97 | 1.89E-14 | Height |
| BLCA | cis | rs10935120 | 1 | rs13089966 | chr3:134279197 | CEP63 | chr3:134204575-134293852:+ | -0.24 | -4.09 | 5.33E-5 | Height |
| BLCA | cis | rs10935120 | 1 | rs13090969 | chr3:134307257 | ANAPC13 | chr3:134196547-134204865:- | -0.5 | -7.94 | 2.24E-14 | Height |
| BLCA | cis | rs10935120 | 1 | rs13090969 | chr3:134307257 | CEP63 | chr3:134204575-134293852:+ | -0.24 | -4.14 | 4.32E-5 | Height |
| BLCA | cis | rs9876781 | 1 | rs13091785 | chr3:48494098 | TREX1 | chr3:48501186-48509043:+ | -0.19 | -3.92 | 0.000105 | Longevity |
| BLCA | cis | rs7611238 | 1 | rs13091924 | chr3:195051136 | C3orf21 | chr3:194789015-194991895:- | 0.29 | 5.61 | 3.97E-8 | Body mass index |